Two-dimensional painting applications can make interesting use of texturing and blending. An arbitrary image can be used as a paint brush, using blending to accumulate the contribution over time. The image source (paint brush) can be geometry or a pixel image. A texture mapped quad under an orthographic projection can be used in the same way as a pixel image and often more efficiently (when texture mapping is hardware accelerated).
An interesting way to implement the painting process is to precompute the
effect of painting the entire image with the brush and then use blending to
selectively expose the painted area as the brush passes over the area. This
can be implemented efficiently with texturing by using the fully painted
image as a texture map, blending the source image mapped on the brush with
the current image stored in the color buffer. Use a
geometric shape and translate the 
texture coordinates as the 
coordinates move across the image. The main advantage of this
technique is that elaborate paint/brush combinations can be efficiently
computed across the entire image all at once rather than performing
localized computations in the area covered by the brush.